Sub-endometrial Platelet-Rich Plasma (PRP) injection is a promising treatment for women with a thin uterine lining that does not respond well to hormonal therapy. A healthy endometrium is crucial for successful embryo implantation, and PRP therapy helps improve its thickness and blood supply. The procedure is simple, safe, and minimally invasive.
The process begins with a small blood sample taken from the patient. This blood is placed in a special machine called a centrifuge, which spins it at high speed to separate the platelet-rich plasma from other components. The PRP contains important growth factors that help heal and regenerate tissues. Once the PRP is ready, the patient is prepared for the injection.
The patient lies in a comfortable position, similar to a routine gynecological exam. A speculum is gently inserted to make the cervix easily accessible. A thin, flexible catheter is then inserted through the cervix into the uterus. The doctor uses ultrasound guidance to ensure that the PRP reaches the right spot, specifically the sub-endometrial layer of the uterus. Once in position, the PRP is slowly injected, allowing the growth factors to work on the uterine lining. The entire process is quick and painless, taking only a few minutes.
After the injection, the patient rests for a short while and can go home the same day. Since the procedure is non-surgical, there is no need for anesthesia, and normal activities can be resumed immediately. A follow-up ultrasound is usually scheduled a few days later to check if the endometrial thickness has improved. In some cases, multiple PRP injections may be needed for the best results.
This treatment is gaining popularity because it stimulates tissue repair, improves blood flow, and enhances endometrial growth. Many women who have struggled with implantation failures or repeated IVF failures have seen positive results after PRP therapy. Since the PRP is made from the patient’s own blood, there is no risk of rejection or serious side effects.
Sub-endometrial PRP injection is a hopeful and effective option for women facing difficulties with conception due to a thin endometrium. It is a simple, natural, and innovative approach that improves the chances of a successful pregnancy